Answers for "pd change entire column with condition on another column"

pandas replace values in column based on condition

In [41]:
df.loc[df['First Season'] > 1990, 'First Season'] = 1
df

Out[41]:
                 Team  First Season  Total Games
0      Dallas Cowboys          1960          894
1       Chicago Bears          1920         1357
2   Green Bay Packers          1921         1339
3      Miami Dolphins          1966          792
4    Baltimore Ravens             1          326
5  San Franciso 49ers          1950         1003

pandas create new column conditional on other columns

# For creating new column with multiple conditions
conditions = [
    (df['Base Column 1'] == 'A') & (df['Base Column 2'] == 'B'),
    (df['Base Column 3'] == 'C')]
choices = ['Conditional Value 1', 'Conditional Value 2']
df['New Column'] = np.select(conditions, choices, default='Conditional Value 1')