Answers for "pandas.read_excel skip unnamed columns"

drop unamed columns in pandas

df = df.loc[:, ~df.columns.str.contains('^Unnamed')]

In [162]: df
Out[162]:
   colA  ColB  colC  colD  colE  colF  colG
0    44    45    26    26    40    26    46
1    47    16    38    47    48    22    37
2    19    28    36    18    40    18    46
3    50    14    12    33    12    44    23
4    39    47    16    42    33    48    38

remove unnamed columns pandas

df2.columns.str.match("Unnamed")
df2.loc[:,~df2.columns.str.match("Unnamed")]