numpy dataframe
pd.DataFrame({"A": [1, 2], "B": [3, 4]}).to_numpy()
array([[1, 3],
[2, 4]])
data = np.array([['','Col1','Col2'],
['Row1',1,2],
['Row2',3,4]])
print(pd.DataFrame(data=data[1:,1:],
index=data[1:,0],
columns=data[0,1:]))