tax query and
$args = array(
'post_type' => 'post',
'tax_query' => array(
'relation' => 'AND',
array(
'taxonomy' => 'movie_genre',
'field' => 'slug',
'terms' => array( 'action', 'comedy' ),
),
array(
'taxonomy' => 'actor',
'field' => 'term_id',
'terms' => array( 103, 115, 206 ),
'operator' => 'NOT IN',
),
),
);
$query = new WP_Query( $args );